Micro-CT for Pharmaceutical Research

X-ray projection stack

SKYSCAN 3D X-ray microscopes are essential tools for R&D and product development in the pharmaceutical field. Accelerate drug development and inspection, increase quality control and gain better insight of defects in manufacturing, or verify packing and coating integrity.  

  • Nano-meter scale resolution for detailed porosity calculations
  • High contrast on low X-ray absorbing phases including active pharmaceutical ingredients and coatings
  • Large field of view for capturing full pharmaceutical tablets
  • Quantitative analysis for pore size, pore size distribution, and volumetric API calculations
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Tablet compression

Full tablet imaging

The large field-of-view detectors of the SkyScan instruments allow for routine scanning of full tablets at high resolution. 

Pharmaceutical - pill delamination

Porosity analysis

Pore size, pores size distribution, and pore orientation are key metrics for understanding the performance of the manufacturing process and the resultant API delivery. These measures can be calculated in the CTAN quantitative analysis program. 

Crack analysis of pill

Crack and delamination analysis

Through the use of the latest detection architecture, the SKYSCAN tomographs can deliver high quality images of internal cracks in the tablet and subsurface delamination of coatings or under debossed regions.  

In-situ compression testing of pill

In-situ compression testing

All SkyScan instruments are pre-wired to accept the in-situ materials testing stages.

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Micro-CT Imaging of Samples Under Mechanical Load

Figure 1: 3D Printed Support Structures After Mechanical Load Testing  As an accessory to the SkyScan instrumentation suite, Bruker offers several interesting accessories that can further support your research goals.

Seth Hogg, PhD August 26, 2021
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Not sure about the best instrument for your application?
Do you want to see micro-CT results of your sample?
Our specialists are happy to help.
Buyers’ Guide
Submit a Sample
Contact Ben
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Customer access to tips and instructional videos, method notes, tutorials, application notes, and other content to support your research.

Employment

While we are not currently looking to fill a specific position at Micro Photonics, if helping others advance their research is something you are passionate about, then feel free to send us your resume so that we can keep it for further considerations when a position does become available.

Please submit resumes to: info@microphotonics.com

Micro Photonics Inc.
1550 Pond Road, STE 110
Allentown, PA 18104

Tel: 1-866-334-4MPI (4674)
        (610) 366-7103
Fax: (610) 366-7105

Events

Due to Covid-19 restrictions, we will not be attending tradeshows in the near future. We are participating in webinars and virtual tradeshows and will post links to those as they are available.

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Terms of Service for www.microphotonics.com

Introduction. Welcome to www.microphotonics.com. This website is owned and operated by Micro Photonics Inc. By visiting our website and accessing the information, resources, services, products, and tools we provide, you understand and agree to accept and adhere to the following terms and conditions as stated in this policy (hereafter referred to as ‘User Agreement’), along with the terms and conditions as stated in our Privacy Policy (please refer to the Privacy Policy section below for more information).

This agreement is in effect as of October 25, 2018.

We reserve the right to change this User Agreement from time to time without notice. You acknowledge and agree that it is your responsibility to review this User Agreement periodically to familiarize yourself with any modifications. Your continued use of this site after such modifications will constitute acknowledgment and agreement of the modified terms and conditions.

Responsible Use and Conduct. By visiting our website and accessing the information, resources, services, products, and tools we provide for you, either directly or indirectly (hereafter referred to as ‘Resources’), you agree to use these Resources only for the purposes intended as permitted by (a) the terms of this User Agreement, (b) the terms of any applicable confidentiality, non-disclosure, or other agreement between you and a third party, and (c) applicable laws, regulations and generally accepted online practices or guidelines.

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Micro-CT Buyers' Guide

Free Micro-CT Evaluation Scan

Are you interested in Micro-CT but aren’t sure if it will work for your application?  We would be happy to help you determine if a micro-CT is right for you and guide you to the system that is best suited for your application.  Our micro-CT laboratory has five different Bruker SkyScan Micro-CT systems available for a thorough investigation of your sample.

Micro-CT results

Send in a sample and our micro-CT experts will do the rest.  We will select the best instrument, scan the sample, and reconstruct the data.  You will receive a series of cross-sectional images visualizing the interior structure, a 3D model of your results and  a video of your sample with cut-through views. We will also provide our visualization software for enhanced viewing in both 2D and 3D … Explore Within!

Fill out the form below and will we contact you to arrange the free micro-CT scan.